The artist has handed over the entirety of his £25,000 honor prize money to the trust for venues, which functions to save the UK's grassroots music venues.
Fender was presented with the award on October 16 as his latest record his work was chosen as the best record of the last 12 months.
Fender has decided to hand the money over to the MVT, in recognition of the essential function local spots had in his early career.
"I personally wouldn't be doing what I am doing today if it wasn't for all the gigs I played around the North East, and further afield, when I was starting out," said Fender. "These locations are iconic, but they are struggling."
Since the start of 2023, at least 150 of these venues have permanently closed – approximately 16% of the whole industry in the UK.
In the last year, well-known musicians such as Pulp, the group Coldplay, the singer Katy Perry and Ed Sheeran have all supported the MVT in its attempts to keep the scene afloat, by adding a minor surcharge to their ticket prices, which benefits independent venues.
Sam Fender also participated, raising in excess of £100,000 on his recent tour to assist numerous grassroots venues across England, Scotland, and Wales.
The donation helped locations that were confronting potential shutdown due to issues caused by water damage, fire incidents and personal losses, as well as permit problems, legal disputes and sound issues.
Some locations received financial assistance in modernizing infrastructure and sound and lighting systems that positively impacted artists and audiences.
"The concept that funds from shows in major spaces backs the independent spots, where it begins for musicians like me, is just common sense," Sam Fender has stated.
The musician is not the first artist to contribute his Mercury Prize prize money to charitable organizations.
Back when they won the award in 1996 for their release their work, frontman Jarvis Cocker declared that the act would donate their prize money to the non-profit War Child.
In 2002, artist she divided her award across multiple organizations, like the NSPCC and a Sickle Cell organization.
"Additionally, I contributed a grand to the center, to their gymnastics class, because I practiced gymnastics when I was younger and they lacked updated gear," Ms Dynamite explained to the media.
In recent years, Ezra Collective gave their funds to the youth organization that nurtured their act, as well as other independent music bodies.
Additionally winners that year the group contributed their winnings to a MS organization after a friend was found to have the illness.
"Winning was sufficient," stated singer the singer. "The prize was the bonus but we could do without the cherry, because we had the cake. So our winning impacted another person's life."
Last week, the Music Venues Trust revealed it had protected a couple of grassroots venues in south-east England, by bringing them into local control.
One venue in Southampton and the second in the city were acquired under the Own Our Venues initiative, which is supported by the arts council and music fans who buy "ownership units" in the properties.